Plasma substance P level in patients with schizophrenia: A cross-sectional study

Takuto Ishida, Hiroyuki Uchida, Takefumi Suzuki, Shinichiro Nakajima, Koichiro Watanabe, Haruo Kashima

研究成果: Article査読

6 被引用数 (Scopus)

抄録

Aspiration pneumonia is a serious health concern in older patients with schizophrenia. In this study, we examined clinical and demographic variables that could impact the plasma substance P level, which is a useful predictive biomarker of aspiration. Thirty-four patients were included (mean age ± SD: 70.9 ± 10.8 years). A greater number of cigarettes/day and a higher antipsychotic dosage were found to be associated with a lower plasma substance P level, while age showed a trend-level effect. This finding suggests the need for intensive observation for prevention of aspiration pneumonia in heavy smokers who are receiving a higher antipsychotic dose in this senior population.

本文言語English
ページ(範囲)526-528
ページ数3
ジャーナルPsychiatry and Clinical Neurosciences
65
5
DOI
出版ステータスPublished - 2011 8月

ASJC Scopus subject areas

  • 神経科学(全般)
  • 神経学
  • 臨床神経学
  • 精神医学および精神衛生

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