Polyurethane surface modification by graft polymerization of acrylamide for reduced protein adsorption and platelet adhesion

Keiji Fujimoto, Hideki Tadokoro, Yohichi Ueda, Yoshito Ikada

研究成果: Article

91 引用 (Scopus)

抜粋

Surface modification of polyurethane by glow-discharge treatment and subsequent graft polymerization of acrylamide was studied. The modified hydrophilic surfaces were characterized by the measurements of dynamic contact angle and ζ potentials and examined for protein adsorption behaviour and platelet adhesion. Data from in vitro and ex vivo experiments indicated a reduction of protein adsorption and platelet adhesion for the hydrophillic graft polymers, the extent of which was correlated to polymer graft density.

元の言語English
ページ(範囲)442-448
ページ数7
ジャーナルBiomaterials
14
発行部数6
DOI
出版物ステータスPublished - 1993 5
外部発表Yes

ASJC Scopus subject areas

  • Bioengineering
  • Ceramics and Composites
  • Biophysics
  • Biomaterials
  • Mechanics of Materials

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