Portable membrane protein chip: Development of membrane protein sensors for environment analysis

Ryuji Kawano, Yutaro Tsuji, Toshihisa Osaki, Koki Kamiya, Norihisa Miki, Yoke Tanaka, Shoji Takeuchi

研究成果: Conference contribution

抄録

This paper describes a portable measurement system using membrane proteins (receptors) for environment analysis (Figure 1). Creatures sense ambient stimulations as eyesight, smell, taste, and so on, using recipient cells with the receptors in the cell membrane. If those congenital sensing mechanism is exploitable in an artificial system, the bio-inspired system will be applied for ultrahigh sensitive and selective sensors. For developing this sensor, we have addressed the stable and the reliable bilayer lipid membrane (BLM) as a platform for the membrane proteins. Double-well chamber with the parylene micropore that has the Ag/AgCl electrodes on the bottom of the chamber allows us to make the portable BLM device. As the results, we demonstrate the channel current recordings of the membrane protein using our portable BLM system at an extreme environment (at the summit of Mt. Fuji, Figure 2a). This proves that our system can be brought the higher mountain and measured the signals in wild environments.

本文言語English
ホスト出版物のタイトルProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
出版社Chemical and Biological Microsystems Society
ページ845-847
ページ数3
ISBN(印刷版)9780979806452
出版ステータスPublished - 2012
イベント16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
継続期間: 2012 10 282012 11 1

出版物シリーズ

名前Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
国/地域Japan
CityOkinawa
Period12/10/2812/11/1

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

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