Possible involvement of central atrial natriuretic polypeptide in regulation of hypothalamo-pituitary-adrenal axis in conscious rats

Hiroshi Itoh, Kazuwa Nakao, Goro Katsuura, Narito Morii, Takayuki Yamada, Shozo Shiono, Makoto Sakamoto, Akira Sugawara, Yoshihiko Saito, Masami Eigyo, Akira Matsushita, Hiroo Imura

研究成果: Article査読

43 被引用数 (Scopus)

抄録

The effects of intracerebroventricular (i.c.v.) administration of angiotensin II (AII) and atrial natriuretic polypeptide (ANP) on the plasma corticosterone level were studied in conscious, unrestrained rats. Although i.c.v. injection of ANP had no apparent effect on the basal plasma corticosterone level, it attenuated the plasma corticosterone increase induced by centrally injected AII dose-dependently. These results suggest that ANP in the brain is involved in the regulation of the hypothalamo-pituitary-adrenal axis.

本文言語English
ページ(範囲)254-258
ページ数5
ジャーナルNeuroscience Letters
69
3
DOI
出版ステータスPublished - 1986 9月 12
外部発表はい

ASJC Scopus subject areas

  • 神経科学(全般)

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