Post-transplant lymphoproliferative disorder of the adrenal gland after allogeneic hematopoietic stem cell transplantation: Report of two cases and literature review

H. Kasahara, T. Mori, J. Kato, Y. Koda, Sumiko Kohashi, T. Kikuchi, M. Sakurai, Y. Yamane, S. Mikami, K. Kameyama, Y. Takahashi, S. Okamoto

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Post-transplant lymphoproliferative disorder (PTLD) is one of the life-threatening complications after hematopoietic stem cell transplantation (HSCT) and solid organ transplantation (SOT), and it is associated almost exclusively with Epstein-Barr virus (EBV). We herein report 2 cases of EBV-associated PTLD after allogeneic HSCT localized in the adrenal gland. Both patients developed adrenal tumor within 3 months after HSCT and were successfully treated with rituximab or tapering immunosuppressive agents. Both remained alive without recurrence. A literature review revealed 12 reported cases of PTLD involving the adrenal gland, but the adrenal gland was involved as one of the lesions of advanced-stage PTLD after SOT. To the best of our knowledge, this is the first report to show cases of isolated EBV-associated adrenal PTLD after HSCT. PTLD should be recognized as one of the causes of isolated adrenal tumor after HSCT.

本文言語English
ページ(範囲)909-914
ページ数6
ジャーナルTransplant Infectious Disease
17
6
DOI
出版ステータスPublished - 2015 12 1

ASJC Scopus subject areas

  • Infectious Diseases
  • Transplantation

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