抄録
Thirty-three crude drug extracts were screened for their tyrosinase inhibitory activity. Among them, the acetone extract of the rhizomes of Rheum officinale Baillon showed the strongest inhibitory activity. Tyrosinase inhibitory activity-guided fractionation and chemical analysis led to the isolation of two potent compounds, 3,4',5-trihydroxystilbene-4'-O-β-D-(2''-O-galloyl)glucopyranoside (1) and 3,4',5-trihydroxystilbene-4'-O-β-D-(6-O-galloyl)glucopyranoside (2). These compounds showed a competitive inhibition against tyrosinase and also inhibited the melanin biosynthesis.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 425-428 |
| ページ数 | 4 |
| ジャーナル | Planta Medica |
| 巻 | 61 |
| 号 | 5 |
| DOI | |
| 出版ステータス | Published - 1995 10月 12 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 分析化学
- 分子医療
- 薬理学
- 薬科学
- 創薬
- 補完代替医療
- 有機化学