抄録
Fuligocandins A and B, cycloanthranilylproline derivatives isolated from the myxomycete Fuligo candida, were synthesized efficiently by a Meyer-Schuster rearrangement, which gave Z-isomer with high selectivity. The absolute stereochemistry at C-11a of the natural products was determined to be S by comparison of the optical rotation of the natural products with synthetic counterparts derived from l-proline. This report is the first total synthesis of optically active fuligocandin B.
本文言語 | English |
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ページ(範囲) | 2498-2502 |
ページ数 | 5 |
ジャーナル | Synlett |
号 | 16 |
DOI | |
出版ステータス | Published - 2010 |
外部発表 | はい |
ASJC Scopus subject areas
- 有機化学