Predicting outcomes of neonates born to GBS-positive women who received inadequate intrapartum antimicrobial prophylaxis

Katsuaki Kojima, Ryuma Tanaka, Keisuke Nakajima, Nobuyoshi Kurihara, Mari S aito Oba, Yukio Yamashita, Jun Ishihara, Naohisa Yahagi

研究成果: Article査読

2 被引用数 (Scopus)

抄録

We determined the predicting factors of early-onset group B streptococcal (EOGBS) infection in neonates who were born to GBS carrier mothers with inadequate intrapartum antibiotic prophylaxis (IAP). Medical records of all neonates born from January 1, 2008 to April 1, 2010 were reviewed. Inadequate IAP was defined as delivery less than 4 hours (h) after the first administration of antimicrobial. Of 1910 neonates, 273 were born from mothers colonized with GBS, including 69 who received inadequate IAP. Of 69 neonates, nine showed symptoms, including respiratory distress, fever, tachycardia, vomiting, and irritability. Abnormalities in complete blood count (CBC) and C-reactive protein (CRP) were noted in three and four neonates, respectively. Three infants were diagnosed with EOGBS infection confirmed by positive rectal and throat cultures, and all three presented with respiratory distress and CRP abnormalities. Respiratory distress (p=0.0004) and CRP (p=0.0001) offered reliable indicators for detecting EOGBS infections.

本文言語English
ページ(範囲)238-242
ページ数5
ジャーナルThe Turkish journal of pediatrics
56
3
出版ステータスPublished - 2014 5 1
外部発表はい

ASJC Scopus subject areas

  • 小児科学、周産期医学および子どもの健康

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