Pregnancy outcomes of reciprocal translocation carriers who have a history of repeated pregnancy loss

Nobuaki Ozawa, Tetsuo Maruyama, Takashi Nagashima, Masanori Ono, Toru Arase, Hitoshi Ishimoto, Yasunori Yoshimura

研究成果: Article査読

35 被引用数 (Scopus)

抄録

Cytogenetic investigation of 2,324 Japanese couples with repeated pregnancy loss revealed that 4.91% of couples (n = 114) had chromosome abnormalities including reciprocal translocation (n = 74), Robertsonian translocation (n = 23), and inversion (n = 10). Parental reciprocal translocation was a significant predictor of subsequent miscarriage (adjusted odds ratio: 3.6, 95% confidence interval: 1.8-7.1), and most of the miscarriages of the carrier couples were inevitable because of abnormal karyotypes, despite appropriate treatments.

本文言語English
ページ(範囲)1301-1304
ページ数4
ジャーナルFertility and Sterility
90
4
DOI
出版ステータスPublished - 2008 10月

ASJC Scopus subject areas

  • 生殖医学
  • 産婦人科学

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