Preoperative combination chemotherapy with TS-1 is effective in a case gastric cancer with peritoneal dissemination

Rieko Nakamura, Yoshiro Saikawa, Tetsuro Kubota, Tetsuya Nakamura, Yukako Akatsu, Tsunehiro Takahashi, Masashi Yoshida, Yoshihide Otani, Koichiro Kumai, Masaki Kitajima

研究成果: Article

1 引用 (Scopus)

抄録

We report a case of peritoneal cancer dissemination with Type 4 gastric cancer, successfully treated with combination chemotherapy with TS-1. The patient was a 59-year-old female, who complained of abdominal distension with pain, weight loss, and poor appetite. She was diagnosed as unresectable Type 4 gastric cancer, T3N2MOHOP1CY1M0, Stage IV with massive ascites (cytology: Class V). After 2 courses of combined chemotherapy with TS-1 and cisplatin (CDDP), primary tumor reduction was confirmed and no cancer cells were detected from a pathological investigation with biopsied specimens by endoscopy. As additional therapy for remained ascites, intraperitoneal administration of paclitaxel and docetaxel was performed, resulting in a remarkable decrease of ascites with cytological disappearance of cancer cells. The patients underwent total gastrectomy with lymph node dissection, pathological diagnosis of primary site and lymph nodes showed grade 2 effect, and no cancer cells were detected in ascites and peritoneum, microscopically. While she died of peritoneal recurrence after the surgery, the case suggested the clinical advantage of controlling the advanced cancer-bearing state by combination chemotherapy with TS-1, instead of surgery.

元の言語English
ページ(範囲)1323-1326
ページ数4
ジャーナルGan to kagaku ryoho. Cancer & chemotherapy
32
発行部数9
出版物ステータスPublished - 2005 9

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Combination Drug Therapy
Stomach Neoplasms
Ascites
Neoplasms
docetaxel
Peritoneum
Appetite
Gastrectomy
Paclitaxel
Lymph Node Excision
Cisplatin
Endoscopy
Cell Biology
titanium silicide
Weight Loss
Lymph Nodes
Recurrence
Drug Therapy
Pain

ASJC Scopus subject areas

  • Cancer Research
  • Pharmacology

これを引用

Nakamura, R., Saikawa, Y., Kubota, T., Nakamura, T., Akatsu, Y., Takahashi, T., ... Kitajima, M. (2005). Preoperative combination chemotherapy with TS-1 is effective in a case gastric cancer with peritoneal dissemination. Gan to kagaku ryoho. Cancer & chemotherapy, 32(9), 1323-1326.

Preoperative combination chemotherapy with TS-1 is effective in a case gastric cancer with peritoneal dissemination. / Nakamura, Rieko; Saikawa, Yoshiro; Kubota, Tetsuro; Nakamura, Tetsuya; Akatsu, Yukako; Takahashi, Tsunehiro; Yoshida, Masashi; Otani, Yoshihide; Kumai, Koichiro; Kitajima, Masaki.

:: Gan to kagaku ryoho. Cancer & chemotherapy, 巻 32, 番号 9, 09.2005, p. 1323-1326.

研究成果: Article

Nakamura, R, Saikawa, Y, Kubota, T, Nakamura, T, Akatsu, Y, Takahashi, T, Yoshida, M, Otani, Y, Kumai, K & Kitajima, M 2005, 'Preoperative combination chemotherapy with TS-1 is effective in a case gastric cancer with peritoneal dissemination', Gan to kagaku ryoho. Cancer & chemotherapy, 巻. 32, 番号 9, pp. 1323-1326.
Nakamura, Rieko ; Saikawa, Yoshiro ; Kubota, Tetsuro ; Nakamura, Tetsuya ; Akatsu, Yukako ; Takahashi, Tsunehiro ; Yoshida, Masashi ; Otani, Yoshihide ; Kumai, Koichiro ; Kitajima, Masaki. / Preoperative combination chemotherapy with TS-1 is effective in a case gastric cancer with peritoneal dissemination. :: Gan to kagaku ryoho. Cancer & chemotherapy. 2005 ; 巻 32, 番号 9. pp. 1323-1326.
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AU - Akatsu, Yukako

AU - Takahashi, Tsunehiro

AU - Yoshida, Masashi

AU - Otani, Yoshihide

AU - Kumai, Koichiro

AU - Kitajima, Masaki

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