We prepared Chromatography matrices having thermoresponisve polymer brush structure by atom transfer radical polymerization (ATRP) of N- isopropylacrylamide (IPAAm) on silica beads. Retention times for steroids extended with increasing grafted PIPAAm amounts controlled by polymerizatuion times. Elution profiles of steroids on column packed with PIPAAm-grafted matrices prepared by ATRP depend largely on the column temperature. This indicates that matrices having thermoresponisve polymer brush layers would be useful for controlling strong hydrophobicity of HPLC stationary phases simply by changing column temperature.
|出版ステータス||Published - 2005 12月 1|
|イベント||54th SPSJ Symposium on Macromolecules - Yamagata, Japan|
継続期間: 2005 9月 20 → 2005 9月 22
|Other||54th SPSJ Symposium on Macromolecules|
|Period||05/9/20 → 05/9/22|
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