Preparation of (R)-ibuprofen and related carboxylic acids using microbial oxidation of an aromatic hydrocarbon by rhodococcus sp. bpm 1613t

Takeshi Sugai; Kenji Mori

doi:10.1080/00021369.1984.10866522

Preparation of (R)-ibuprofen and related carboxylic acids using microbial oxidation of an aromatic hydrocarbon by rhodococcus sp. bpm 1613t

研究成果: Article › 査読

抄録

(R)-2-(4'-Isobutylphenyl)propanoic acid (ibuprofen), (S’)-3-(4'-isobutylphenyl)butanoic acid and (S)-4-(4'-isobutylphenyl)pentanoic acid were obtained using microbial oxidation of (±)-l- isobutyl-4-(1'-methyloctyl)benzene by Rhodococcus sp. BPM 1613.

本文言語	English
ページ（範囲）	2501-2504
ページ数	4
ジャーナル	Agricultural and biological chemistry
巻	48
号	10
DOI	https://doi.org/10.1080/00021369.1984.10866522
出版ステータス	Published - 1984 10月
外部発表	はい

ASJC Scopus subject areas

生化学、遺伝学、分子生物学（全般）
農業および生物科学（全般）

文献へのアクセス

10.1080/00021369.1984.10866522

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引用スタイル

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title = "Preparation of (R)-ibuprofen and related carboxylic acids using microbial oxidation of an aromatic hydrocarbon by rhodococcus sp. bpm 1613t",

abstract = "(R)-2-(4'-Isobutylphenyl)propanoic acid (ibuprofen), (S{\textquoteright})-3-(4'-isobutylphenyl)butanoic acid and (S)-4-(4'-isobutylphenyl)pentanoic acid were obtained using microbial oxidation of (±)-l- isobutyl-4-(1'-methyloctyl)benzene by Rhodococcus sp. BPM 1613.",

author = "Takeshi Sugai and Kenji Mori",

note = "Funding Information: Acknowledgments. We thank Dr. K. Nakajima, Fermentation Research Institute, Agency of Industrial Science and Technology, Tsukuba, for his kind gift of Rhodococcus sp. BPM 1613 and helpful discussion on our experiments. We acknowledge with thanks the helpful discussion with Professor Y. Minoda and Dr. T. Omori of this Department. Our thanks are due to Mr. H. Watanabe, for his measurement of 13C-NMR spectra, and Dr. K. Okada, for his gift of an authentic sample of ibuprofen.",

year = "1984",

month = oct,

doi = "10.1080/00021369.1984.10866522",

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AU - Sugai, Takeshi

AU - Mori, Kenji

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PY - 1984/10

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N2 - (R)-2-(4'-Isobutylphenyl)propanoic acid (ibuprofen), (S’)-3-(4'-isobutylphenyl)butanoic acid and (S)-4-(4'-isobutylphenyl)pentanoic acid were obtained using microbial oxidation of (±)-l- isobutyl-4-(1'-methyloctyl)benzene by Rhodococcus sp. BPM 1613.

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