Preparation of spherical porous granules composed of rod-shaped hydroxyapatite and evaluation of their protein adsorption properties

Toshiharu Takahashai, Masanobu Kamitakahara, Giichiro Kawachi, Koji Ioku

研究成果: Article

9 引用 (Scopus)

抜粋

The present study examined the possibility of using spherical porous granules of hydroxyapatite (HA, Ca10(PO4) 6(OH)2) composed of rod-shaped particles as the drug delivery system. The granules composed of rod-shaped HA were successfully prepared by an emulsion method and a hydrothermal treatment When the rod-shaped granules were soaked in phosphate buffer salines containing lysozyme chloride or albumin, the granules of rod-shaped HA adsorbed more albumin than lysozyme. On the other hand, the HA granules prepared by a normal sintering method adsorbed little lysozyme chloride or albumin. The HA granules composed of rod-shaped particles are expected to be useful as carriers of negatively charged substances.

元の言語English
ページ(範囲)83-86
ページ数4
ジャーナルKey Engineering Materials
361-363 I
出版物ステータスPublished - 2008 1 1
外部発表Yes

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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