@article{c94eaefac8e0483cb7bc2cab98d2e9df,
title = "Presynaptic M1 muscarinic receptor modulates spontaneous release of acetylcholine from rat basal forebrain slices",
abstract = "Spontaneous release of acetylcholine (ACh) from rat basal forebrain slices in the presence of cholinesterase inhibitor was directly determined using a specific radioimmunoassay for ACh. The release was calcium dependent. A consistent amount of ACh release was observed throughout the experiment. Atropine (10-8 to 10-5 M) and pirenzepine (10-7 to 10-5 M) enhanced spontaneous ACh release. These findings indicate the presence of an M1 muscarinic autoreceptor that modulates spontaneous release of ACh in the rat basal forebrain.",
keywords = "Acetylcholine release, Atropine, Autoreceptor, Basal forebrain, M muscarinic receptor, Pirenzepine, Radioimmunoassay",
author = "Takeshi Suzuki and Kazuko Fujimoto and Hisayo Oohata and Koichiro Kawashima",
note = "Funding Information: This work was supportedin part by a Grant from The Fujisawa Foundationfo r 1987.W e are gratefult o Ms. Misao Hisada, Ms. Tomoko Miyagawaa nd Ms. Akiko Nagoshi for their technicaal ssistance.",
year = "1988",
month = jan,
day = "22",
doi = "10.1016/0304-3940(88)90409-0",
language = "English",
volume = "84",
pages = "209--212",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "2",
}