Prognostic value of a qualitative test for heart-type fatty acid-binding protein in patients with acute coronary syndrome

Masaru Suzuki, Shingo Hori, Shigetaka Noma, Kenji Kobayashi

研究成果: Article

20 引用 (Scopus)

抄録

Heart-type fatty acid-binding protein (h-FABP) is a novel diagnostic marker for myocardial infarction, but its prognostic value has not been established in patients with acute coronary syndrome (ACS). We sought to determine the value of qualitative analysis of h-FABP for predicting 30-day adverse events in patients with ACS. A retrospective observational study was conducted on patients at a community hospital, and 130 patients admitted through the emergency room (ER) for ACS were identified among 12,077 patients who presented to the ER between January and June 2003. Of these 130 patients, 90 (mean age, 66.8 years, 67 males) who had ACS were eligible for this study. Qualitative tests for serum h-FABP and troponin T (cTnT) were performed on presentation. Follow-up information on adverse events within 30 days after admission, defined as cardiac death or recurrent ACS, was obtained from the medical records. The qualitative tests for h-FABP and troponin T were positive in 62.2% and 36.7%, respectively. The cumulative adverse event rate at 30 days was 14.8% in the h-FABP-positive group and 3.2% in the negative group. The adjusted relative risk of a positive h-FABP test for adverse events was 44.98 (95% CI: 1.48 to 1364.88). A positive h-FABP test was an independent predictor of adverse events within 30 days in these patients.

元の言語English
ページ(範囲)601-606
ページ数6
ジャーナルInternational Heart Journal
46
発行部数4
DOI
出版物ステータスPublished - 2005 9 13
外部発表Yes

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Fatty Acid-Binding Proteins
Acute Coronary Syndrome
Troponin T
Hospital Emergency Service
Community Hospital
Medical Records
Observational Studies
Retrospective Studies
Myocardial Infarction
Serum

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

これを引用

Prognostic value of a qualitative test for heart-type fatty acid-binding protein in patients with acute coronary syndrome. / Suzuki, Masaru; Hori, Shingo; Noma, Shigetaka; Kobayashi, Kenji.

:: International Heart Journal, 巻 46, 番号 4, 13.09.2005, p. 601-606.

研究成果: Article

Suzuki, Masaru ; Hori, Shingo ; Noma, Shigetaka ; Kobayashi, Kenji. / Prognostic value of a qualitative test for heart-type fatty acid-binding protein in patients with acute coronary syndrome. :: International Heart Journal. 2005 ; 巻 46, 番号 4. pp. 601-606.
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