抄録
Propolis is a glue, prepared by honeybees from plant materials to stick their hives on the beehive wall. It has gained popularity in Japan as a healthy drink and people believe that propolis can cure inflammation, heart diseases and even diabetes and cancer. We have evaluated the β-cell protective effect of propolis against the toxicity of streptozotocin (STZ) in rats. The water extract of propolis (PWE) completely protected β-cell destruction against STZ toxicity. The protective effect of PWE was found to be almost equal to that of nicotinamide. PWE also inhibited the interleukin-1 ß(IL-I ß) generation from human leukocytes. The free radical scavenging activity to-gether with IL-I ßand nitric oxide (NO) synthase inhibitory activities are thought to be the prime factors for the protective effect of PWE against STZ toxicity.
本文言語 | English |
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ページ(範囲) | 203-209 |
ページ数 | 7 |
ジャーナル | Phytomedicine |
巻 | 3 |
号 | 2 |
DOI | |
出版ステータス | Published - 1996 9月 |
外部発表 | はい |
ASJC Scopus subject areas
- 分子医療
- 薬理学
- 薬科学
- 創薬
- 補完代替医療