PSA nadir after 125I prostate brachytherapy

Atsunori Yorozu; K. Toya; K. Yoshida; N. Koike; A. Takahashi; S. Saito; T. Nishiyama; Y. Yagi; R. Namitome; A. Ashikari; T. Kono

PSA nadir after ¹²⁵I prostate brachytherapy

Atsunori Yorozu, K. Toya, K. Yoshida, N. Koike, A. Takahashi, S. Saito, T. Nishiyama, Y. Yagi, R. Namitome, A. Ashikari, T. Kono

研究成果: Article › 査読

抄録

To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent ¹²⁵I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.

本文言語	English
ページ（範囲）	793-796
ページ数	4
ジャーナル	Japanese Journal of Clinical Radiology
巻	57
号	6
出版ステータス	Published - 2012 6月 10
外部発表	はい

ASJC Scopus subject areas

放射線学、核医学およびイメージング

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title = "PSA nadir after 125I prostate brachytherapy",

abstract = "To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent 125I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.",

author = "Atsunori Yorozu and K. Toya and K. Yoshida and N. Koike and A. Takahashi and S. Saito and T. Nishiyama and Y. Yagi and R. Namitome and A. Ashikari and T. Kono",

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T1 - PSA nadir after 125I prostate brachytherapy

AU - Yorozu, Atsunori

AU - Toya, K.

AU - Yoshida, K.

AU - Koike, N.

AU - Takahashi, A.

AU - Saito, S.

AU - Nishiyama, T.

AU - Yagi, Y.

AU - Namitome, R.

AU - Ashikari, A.

AU - Kono, T.

PY - 2012/6/10

Y1 - 2012/6/10

N2 - To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent 125I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.

AB - To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent 125I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.

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PSA nadir after 125I prostate brachytherapy

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ASJC Scopus subject areas

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PSA nadir after ¹²⁵I prostate brachytherapy