To evaluate the prostate-specific antigen (PSA) kinetics and nadir of PSA failure after permanent 125I prostate brachytherapy. The study included 660 patients with a potential minimum follow-up of 5 years. Patients who met the Phoenix definition of PSA failure were identified. The PSA decreased gradually to less than 0.2ng/mL even after 5 years for many patients. The median PSA nadir was 0.09ng/mL. Neoadjuvant hormone therapy had little effect on PSA nadir. The PSA nadir < = 0.2ng/mL or current nadir < = 0.4ng/mL seemed to be a good marker as a successful treatment.
|ジャーナル||Japanese Journal of Clinical Radiology|
|出版物ステータス||Published - 2012 6 10|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging