Quantitative evaluation of tear meniscus height from fluorescein photographs

Masataka Kawai, Masakazu Yamada, Motoko Kawashima, Makoto Inoue, Eiki Goto, Yukihiko Mashima, Kazuo Tsubota

研究成果: Article

23 引用 (Scopus)

抄録

PURPOSE: To describe a method of quantifying the tear meniscus height (TMH) and using these values to diagnose patients with dry eye. METHODS: Thirty-eight eyes of 19 healthy subjects and 14 patients diagnosed with dry eye were studied. Each eye received 2 μL of 1% fluorescein-sodium solution in the conjunctival sac, and digital photographs were taken of the external surface of the eye with a fundus camera. The tear meniscus was extracted from the digitalized image and used to measure the TMH with NIH image software. The correlation between the mean TMH and Schirmer test values or cotton-thread test values was evaluated. RESULTS: The means of the upper and lower TMH in healthy subjects were 0.22 ± 0.06 and 0.24 ± 0.08 mm, respectively. The comparable values in patients with dry eye were 0.17 ± 0.04 and 0.17 ± 0.07 mm (upper TMS, P = 0.01; lower TMH, P = 0.04; unpaired t test). A significant correlation was found between the TMH and Schirmer test values (r = 0.72, P = 0.01) but not with cotton-thread test values. CONCLUSIONS: Fluorescein photographs of the eye can be used to quantify the upper and lower TMH separately and simultaneously without specialized equipment. This technique can be used for the diagnosis of dry eye.

元の言語English
ページ(範囲)403-406
ページ数4
ジャーナルCornea
26
発行部数4
DOI
出版物ステータスPublished - 2007 5

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Fluorescein
Tears
Healthy Volunteers
Lacrimal Apparatus
Meniscus
Software
Equipment and Supplies

ASJC Scopus subject areas

  • Ophthalmology

これを引用

Kawai, M., Yamada, M., Kawashima, M., Inoue, M., Goto, E., Mashima, Y., & Tsubota, K. (2007). Quantitative evaluation of tear meniscus height from fluorescein photographs. Cornea, 26(4), 403-406. https://doi.org/10.1097/ICO.0b013e318033c242

Quantitative evaluation of tear meniscus height from fluorescein photographs. / Kawai, Masataka; Yamada, Masakazu; Kawashima, Motoko; Inoue, Makoto; Goto, Eiki; Mashima, Yukihiko; Tsubota, Kazuo.

:: Cornea, 巻 26, 番号 4, 05.2007, p. 403-406.

研究成果: Article

Kawai, M, Yamada, M, Kawashima, M, Inoue, M, Goto, E, Mashima, Y & Tsubota, K 2007, 'Quantitative evaluation of tear meniscus height from fluorescein photographs', Cornea, 巻. 26, 番号 4, pp. 403-406. https://doi.org/10.1097/ICO.0b013e318033c242
Kawai M, Yamada M, Kawashima M, Inoue M, Goto E, Mashima Y その他. Quantitative evaluation of tear meniscus height from fluorescein photographs. Cornea. 2007 5;26(4):403-406. https://doi.org/10.1097/ICO.0b013e318033c242
Kawai, Masataka ; Yamada, Masakazu ; Kawashima, Motoko ; Inoue, Makoto ; Goto, Eiki ; Mashima, Yukihiko ; Tsubota, Kazuo. / Quantitative evaluation of tear meniscus height from fluorescein photographs. :: Cornea. 2007 ; 巻 26, 番号 4. pp. 403-406.
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AU - Kawai, Masataka

AU - Yamada, Masakazu

AU - Kawashima, Motoko

AU - Inoue, Makoto

AU - Goto, Eiki

AU - Mashima, Yukihiko

AU - Tsubota, Kazuo

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N2 - PURPOSE: To describe a method of quantifying the tear meniscus height (TMH) and using these values to diagnose patients with dry eye. METHODS: Thirty-eight eyes of 19 healthy subjects and 14 patients diagnosed with dry eye were studied. Each eye received 2 μL of 1% fluorescein-sodium solution in the conjunctival sac, and digital photographs were taken of the external surface of the eye with a fundus camera. The tear meniscus was extracted from the digitalized image and used to measure the TMH with NIH image software. The correlation between the mean TMH and Schirmer test values or cotton-thread test values was evaluated. RESULTS: The means of the upper and lower TMH in healthy subjects were 0.22 ± 0.06 and 0.24 ± 0.08 mm, respectively. The comparable values in patients with dry eye were 0.17 ± 0.04 and 0.17 ± 0.07 mm (upper TMS, P = 0.01; lower TMH, P = 0.04; unpaired t test). A significant correlation was found between the TMH and Schirmer test values (r = 0.72, P = 0.01) but not with cotton-thread test values. CONCLUSIONS: Fluorescein photographs of the eye can be used to quantify the upper and lower TMH separately and simultaneously without specialized equipment. This technique can be used for the diagnosis of dry eye.

AB - PURPOSE: To describe a method of quantifying the tear meniscus height (TMH) and using these values to diagnose patients with dry eye. METHODS: Thirty-eight eyes of 19 healthy subjects and 14 patients diagnosed with dry eye were studied. Each eye received 2 μL of 1% fluorescein-sodium solution in the conjunctival sac, and digital photographs were taken of the external surface of the eye with a fundus camera. The tear meniscus was extracted from the digitalized image and used to measure the TMH with NIH image software. The correlation between the mean TMH and Schirmer test values or cotton-thread test values was evaluated. RESULTS: The means of the upper and lower TMH in healthy subjects were 0.22 ± 0.06 and 0.24 ± 0.08 mm, respectively. The comparable values in patients with dry eye were 0.17 ± 0.04 and 0.17 ± 0.07 mm (upper TMS, P = 0.01; lower TMH, P = 0.04; unpaired t test). A significant correlation was found between the TMH and Schirmer test values (r = 0.72, P = 0.01) but not with cotton-thread test values. CONCLUSIONS: Fluorescein photographs of the eye can be used to quantify the upper and lower TMH separately and simultaneously without specialized equipment. This technique can be used for the diagnosis of dry eye.

KW - Dry eye

KW - Fluorescein

KW - Fundus camera

KW - Tear meniscus

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