Rapid decline in renal function after acute myocardial infarction

Yusuke Mashima, Tsuneo Konta, Kazunobu Ichikawa, Ami Ikeda, Kazuko Suzuki, Masahiro Wanezaki, Satoshi Nishiyama, Tetsu Watanabe, Isao Kubota

研究成果: Article

4 引用 (Scopus)

抄録

Aim: To investigate the long term effects of cardiac events on renal function, a prospective study of patients with acute myocardial infarction was conducted. Methods: A total of 137 patients with acute myocardial infarction were followed for 1 year. The change of estimated glomerular filtration rate (eGFR) in cardiac patients was compared with that in background-matched controls, and the factors associated with eGFR changes were analyzed. Results: The eGFR decrease was much larger after myocardial infarction, from 73.7 ± 1.9 ml/ min/1.73 m2 (mean ± SEM) at baseline to 64.7 ± 1.7 at 1 year, (p <0.001), compared with that of controls (from 72.8 ± 1.2 to 72.1 ± 1.3, p = 0.305). Multiple regression analysis showed that eGFR change was associated negatively with age, baseline eGFR, proteinuria, and positively with the administration of angiotensin converting enzyme inhibitors or angiotensin II receptor blockers, but not the severity of cardiac damage and comorbidities. Longitudinal analysis 1 year before and 2 years after myocardial infarction showed that eGFR decrease was larger during baseline and 6 months after the event (-7.0 ± 1.0). Conclusions: Renal decline was rapid after myocardial infarction and was affected by clinical characteristics of patients. Careful follow-up of renal function is recommended to prevent the progression of renal and cardiac disease

元の言語English
ページ(範囲)15-20
ページ数6
ジャーナルClinical Nephrology
79
発行部数1
DOI
出版物ステータスPublished - 2013
外部発表Yes

Fingerprint

Glomerular Filtration Rate
Myocardial Infarction
Kidney
Angiotensin Receptor Antagonists
Proteinuria
Angiotensin-Converting Enzyme Inhibitors
Comorbidity
Heart Diseases
Regression Analysis
Prospective Studies

ASJC Scopus subject areas

  • Nephrology

これを引用

Mashima, Y., Konta, T., Ichikawa, K., Ikeda, A., Suzuki, K., Wanezaki, M., ... Kubota, I. (2013). Rapid decline in renal function after acute myocardial infarction. Clinical Nephrology, 79(1), 15-20. https://doi.org/10.5414/CN107645

Rapid decline in renal function after acute myocardial infarction. / Mashima, Yusuke; Konta, Tsuneo; Ichikawa, Kazunobu; Ikeda, Ami; Suzuki, Kazuko; Wanezaki, Masahiro; Nishiyama, Satoshi; Watanabe, Tetsu; Kubota, Isao.

:: Clinical Nephrology, 巻 79, 番号 1, 2013, p. 15-20.

研究成果: Article

Mashima, Y, Konta, T, Ichikawa, K, Ikeda, A, Suzuki, K, Wanezaki, M, Nishiyama, S, Watanabe, T & Kubota, I 2013, 'Rapid decline in renal function after acute myocardial infarction', Clinical Nephrology, 巻. 79, 番号 1, pp. 15-20. https://doi.org/10.5414/CN107645
Mashima Y, Konta T, Ichikawa K, Ikeda A, Suzuki K, Wanezaki M その他. Rapid decline in renal function after acute myocardial infarction. Clinical Nephrology. 2013;79(1):15-20. https://doi.org/10.5414/CN107645
Mashima, Yusuke ; Konta, Tsuneo ; Ichikawa, Kazunobu ; Ikeda, Ami ; Suzuki, Kazuko ; Wanezaki, Masahiro ; Nishiyama, Satoshi ; Watanabe, Tetsu ; Kubota, Isao. / Rapid decline in renal function after acute myocardial infarction. :: Clinical Nephrology. 2013 ; 巻 79, 番号 1. pp. 15-20.
@article{0fdd788895c342ffa31fb25a0c716cb4,
title = "Rapid decline in renal function after acute myocardial infarction",
abstract = "Aim: To investigate the long term effects of cardiac events on renal function, a prospective study of patients with acute myocardial infarction was conducted. Methods: A total of 137 patients with acute myocardial infarction were followed for 1 year. The change of estimated glomerular filtration rate (eGFR) in cardiac patients was compared with that in background-matched controls, and the factors associated with eGFR changes were analyzed. Results: The eGFR decrease was much larger after myocardial infarction, from 73.7 ± 1.9 ml/ min/1.73 m2 (mean ± SEM) at baseline to 64.7 ± 1.7 at 1 year, (p <0.001), compared with that of controls (from 72.8 ± 1.2 to 72.1 ± 1.3, p = 0.305). Multiple regression analysis showed that eGFR change was associated negatively with age, baseline eGFR, proteinuria, and positively with the administration of angiotensin converting enzyme inhibitors or angiotensin II receptor blockers, but not the severity of cardiac damage and comorbidities. Longitudinal analysis 1 year before and 2 years after myocardial infarction showed that eGFR decrease was larger during baseline and 6 months after the event (-7.0 ± 1.0). Conclusions: Renal decline was rapid after myocardial infarction and was affected by clinical characteristics of patients. Careful follow-up of renal function is recommended to prevent the progression of renal and cardiac disease",
keywords = "Cardiac event, Chronic kidney disease, Glomerular filtration rate, Myocardial infarction, Renal failure",
author = "Yusuke Mashima and Tsuneo Konta and Kazunobu Ichikawa and Ami Ikeda and Kazuko Suzuki and Masahiro Wanezaki and Satoshi Nishiyama and Tetsu Watanabe and Isao Kubota",
year = "2013",
doi = "10.5414/CN107645",
language = "English",
volume = "79",
pages = "15--20",
journal = "Clinical Nephrology",
issn = "0301-0430",
publisher = "Dustri-Verlag Dr. Karl Feistle",
number = "1",

}

TY - JOUR

T1 - Rapid decline in renal function after acute myocardial infarction

AU - Mashima, Yusuke

AU - Konta, Tsuneo

AU - Ichikawa, Kazunobu

AU - Ikeda, Ami

AU - Suzuki, Kazuko

AU - Wanezaki, Masahiro

AU - Nishiyama, Satoshi

AU - Watanabe, Tetsu

AU - Kubota, Isao

PY - 2013

Y1 - 2013

N2 - Aim: To investigate the long term effects of cardiac events on renal function, a prospective study of patients with acute myocardial infarction was conducted. Methods: A total of 137 patients with acute myocardial infarction were followed for 1 year. The change of estimated glomerular filtration rate (eGFR) in cardiac patients was compared with that in background-matched controls, and the factors associated with eGFR changes were analyzed. Results: The eGFR decrease was much larger after myocardial infarction, from 73.7 ± 1.9 ml/ min/1.73 m2 (mean ± SEM) at baseline to 64.7 ± 1.7 at 1 year, (p <0.001), compared with that of controls (from 72.8 ± 1.2 to 72.1 ± 1.3, p = 0.305). Multiple regression analysis showed that eGFR change was associated negatively with age, baseline eGFR, proteinuria, and positively with the administration of angiotensin converting enzyme inhibitors or angiotensin II receptor blockers, but not the severity of cardiac damage and comorbidities. Longitudinal analysis 1 year before and 2 years after myocardial infarction showed that eGFR decrease was larger during baseline and 6 months after the event (-7.0 ± 1.0). Conclusions: Renal decline was rapid after myocardial infarction and was affected by clinical characteristics of patients. Careful follow-up of renal function is recommended to prevent the progression of renal and cardiac disease

AB - Aim: To investigate the long term effects of cardiac events on renal function, a prospective study of patients with acute myocardial infarction was conducted. Methods: A total of 137 patients with acute myocardial infarction were followed for 1 year. The change of estimated glomerular filtration rate (eGFR) in cardiac patients was compared with that in background-matched controls, and the factors associated with eGFR changes were analyzed. Results: The eGFR decrease was much larger after myocardial infarction, from 73.7 ± 1.9 ml/ min/1.73 m2 (mean ± SEM) at baseline to 64.7 ± 1.7 at 1 year, (p <0.001), compared with that of controls (from 72.8 ± 1.2 to 72.1 ± 1.3, p = 0.305). Multiple regression analysis showed that eGFR change was associated negatively with age, baseline eGFR, proteinuria, and positively with the administration of angiotensin converting enzyme inhibitors or angiotensin II receptor blockers, but not the severity of cardiac damage and comorbidities. Longitudinal analysis 1 year before and 2 years after myocardial infarction showed that eGFR decrease was larger during baseline and 6 months after the event (-7.0 ± 1.0). Conclusions: Renal decline was rapid after myocardial infarction and was affected by clinical characteristics of patients. Careful follow-up of renal function is recommended to prevent the progression of renal and cardiac disease

KW - Cardiac event

KW - Chronic kidney disease

KW - Glomerular filtration rate

KW - Myocardial infarction

KW - Renal failure

UR - http://www.scopus.com/inward/record.url?scp=84873707656&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84873707656&partnerID=8YFLogxK

U2 - 10.5414/CN107645

DO - 10.5414/CN107645

M3 - Article

C2 - 22909784

AN - SCOPUS:84873707656

VL - 79

SP - 15

EP - 20

JO - Clinical Nephrology

JF - Clinical Nephrology

SN - 0301-0430

IS - 1

ER -