Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by 1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress

Medicine & Life Sciences

• 1,2-naphthoquinone 100%
• Sulfenic Acids 99%
• Sulfur 62%
• 1,2-dihydroxynaphthalene 55%
• Sulfhydryl Compounds 43%
• Oxidative Stress 39%
• Disulfides 28%
• dimedone 26%
• persulfides 24%
• polysulfide 23%
• Reactive Oxygen Species 21%
• Proteins 19%
• Buthionine Sulfoximine 18%
• Hydrogen Sulfide 17%
• Ethylene Glycol 16%
• Ether 14%
• Anions 14%
• Catalase 12%
• Oxidation-Reduction 12%
• Glutathione 12%
• Genes 5%

Chemical Compounds

• 1,2-Naphthoquinone 84%
• Sulfenic Acid 76%
• Oxidative Stress 52%
• Reactive Oxygen Metabolite 25%
• Thiol 22%
• Reactive Sulfur Species 22%
• Protein 22%
• Disulfide 21%
• Adduct 18%
• Hydrogen Sulfide 13%
• Disproportionation 13%
• Electrophile 13%
• Glutathione 11%
• Poly(ethylene Glycol) 10%
• Cleavage 9%
• Ether 9%
• Anion 7%
• Modification 7%
• Reaction Yield 5%