Recent examples of the use of biocatalysts with high accessibility and availability in natural product synthesis

研究成果: Review article査読

11 被引用数 (Scopus)

抄録

Utilization of biocatalysts with high accessibility and availability, which have recently been applied in the preparation of enantiomerically enriched starting materials and synthetic intermediates for natural product syntheses (mainly 2013–2017) are summarized in this review. The main contents are as follows: 1) recruitment of biocatalysts for the transformation of organic compounds; 2) special precautions for preparative-scale biocatalytic synthetic experiments; 3) asymmetric reduction of carbonyl substrates; 4) kinetic resolution of alcohol and carboxylate enantiomers; 5) desymmetrization of multifunctional alcohol and carboxylate substrates; and 6) recognition of remote and non-central chirality.

本文言語English
ページ(範囲)3469-3487
ページ数19
ジャーナルTetrahedron
74
27
DOI
出版ステータスPublished - 2018 7 5

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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