Reduced levels of MMP-2 and TIMP-1 in dyssegmental dysplasia

Kiyoshi Uchide, Hirohisa Ueno, Noboru Takizawa, Yasunori Okada

研究成果: Article › 査読

2 被引用数 (Scopus)

抄録

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) were measured in a mild case of dyssegmental dysplasia. X-ray pictures of a female baby born vaginally at 39 weeks of gestation showed short, bent, dumbbell-shaped long bones of the limbs and profound dyssegmental ossification in the spine, findings characteristic of dyssegmental dysplasia. When the levels of MMP-1, MMP-2, MMP-9, TIMP-1, and TIMP-2 were measured, the levels of MMP-2 and TIMP-1 were significantly reduced. This case might provide a clue to disclose the etiology of dyssegmental dysplasia.

本文言語English
ページ（範囲）381-382
ページ数2
ジャーナルJournal of Bone and Mineral Research
巻18
号2
DOI
出版ステータスPublished - 2003 2 1
外部発表はい

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine

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