Refractory IgG4-related pleural disease with chylothorax: A case report and literature review

Komei Sakata, Jun Kikuchi, Katsura Emoto, Tomomi Kotaki, Yuichiro Ota, Naoshi Nishina, Hironari Hanaoka, Kotaro Otomo, Katsuya Suzuki, Yuko Kaneko, Tsutomu Takeuchi

研究成果: Article査読

1 被引用数 (Scopus)

抄録

We herein report a rare case of a 66-year-old man with refractory chylothorax. Although he had been treated with moderate doses of prednisolone (PSL) on suspicion of pleuritis with Sjögren syndrome, the pleural effusion expanded after the reduction of PSL. Further workup including histopathological examinations of pleura led to the diagnosis of IgG4-RD with bilateral chylothorax without any leakage from the thoracic duct. Combination therapy with high-dose PSL plus rituximab successfully decreased the pleural effusion. This is a very rare case of IgG4-related pleuritis with chylothorax and the first report of its successful treatment with rituximab.

本文言語English
ページ(範囲)2135-2143
ページ数9
ジャーナルInternal Medicine
60
13
DOI
出版ステータスPublished - 2021

ASJC Scopus subject areas

  • 内科学

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