Regulatory T cells and inflammatory bowel diseases

Takanori Kanai, Mamoru Watanabe

研究成果: Article

1 引用 (Scopus)

抜粋

Crohn’s disease and ulcerative colitis are two major forms of human inflammatory bowel diseases (IBD). Their etiology is unknown, but increasing evidence indicate that immune mechanisms play an important role. It is well known that immune responses in the intestine remain in a state of controlled inflammation, suggesting that not only active suppression by regulatory T (TR) cells plays an important role in the normal intestinal homeostasis, but also its dysregula-tion leads to the development of IBD. This article reviews the unique aspects of TR cells and discuss how these control the intestinal homeostasis.

元の言語English
ページ(範囲)302-308
ページ数7
ジャーナルJapanese Journal of Clinical Immunology
27
発行部数5
DOI
出版物ステータスPublished - 2004 1 1
外部発表Yes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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