RELIABLE RE-FORMATION OF A LIPID BILAYER USING A GEOMETRICALLY GUIDED AIR BUBBLE

Izumi Hashimoto, Toshihisa Osaki, Hirotaka Sugiura, Hisatoshi Mimura, Norihisa Miki, Shoji Takeuchi

研究成果: Conference contribution

抄録

This paper reports successful re-formation of a lipid bilayer using an air bubble. Lipid bilayers have been used for membrane protein studies and biosensor applications. Droplet-contact-method is a simple and effective method to form the bilayers. A major challenge in using the bilayers originates from their vulnerability against physical and electrical disturbance, which leads the bilayer rapture and the droplet fusion. We previously proposed a concept to re-form a bilayer by introducing an air bubble to cut-and-split the merged droplet. In this work, we investigated the key parameters to guide the bubble and drastically enhanced the yield up to 97%.

本文言語English
ホスト出版物のタイトルMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Chemical and Biological Microsystems Society
ページ351-352
ページ数2
ISBN(電子版)9781733419031
出版ステータスPublished - 2021
イベント25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
継続期間: 2021 10月 102021 10月 14

出版物シリーズ

名前MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
国/地域United States
CityPalm Springs, Virtual
Period21/10/1021/10/14

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 化学工学(その他)

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引用スタイル