TY - JOUR
T1 - Removal of sodium ion from bile acid solution using diffusional dialysis with cation exchange membrane
AU - Inoue, Hiroyoshi
N1 - Funding Information:
This work was partly supported by a Grant-in-Aid for Scientific Research (No. 14580543) from the Japan Society for the Promotion of Science, and by the Salt Science Research Foundation (No. 0102). The author wishes to thank Tokuyama Corp, Japan for supplying the Neocepta CM1 membrane and Mayumi Kagoshima for her excellent technical assistance.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2003/10/1
Y1 - 2003/10/1
N2 - The behavior of sodium ions passing through a CM1 cation exchange membrane was studied with electroconductive and diffusional membrane permeabilities based on nonequilibrium thermodynamics to remove sodium ion from bile acid solution. These membrane permeabilities of sodium ion in order of amplitude showed sodium chloride > sodiumtaurocholate > sodium cholate systems in all cases. In the sodium cholate and sodium taurocholate systems, the curves relating the electroconductive membrane permeability with concentration showed distinct changes in gradient at around the concentration of primary micelle formation of each bile acid solution. This was attributable to an increase in membrane/solution distribution of bile acid anion on basis of the micelle formation. Using diffusional dialysis, 7.3% of sodium ion was removed from rat serum. Sodium ion was significantly reduced with increasing total bile acid concentration in rat serum (P <0.05; correlation coefficient=-0.606).
AB - The behavior of sodium ions passing through a CM1 cation exchange membrane was studied with electroconductive and diffusional membrane permeabilities based on nonequilibrium thermodynamics to remove sodium ion from bile acid solution. These membrane permeabilities of sodium ion in order of amplitude showed sodium chloride > sodiumtaurocholate > sodium cholate systems in all cases. In the sodium cholate and sodium taurocholate systems, the curves relating the electroconductive membrane permeability with concentration showed distinct changes in gradient at around the concentration of primary micelle formation of each bile acid solution. This was attributable to an increase in membrane/solution distribution of bile acid anion on basis of the micelle formation. Using diffusional dialysis, 7.3% of sodium ion was removed from rat serum. Sodium ion was significantly reduced with increasing total bile acid concentration in rat serum (P <0.05; correlation coefficient=-0.606).
KW - Cation exchange membrane
KW - Cholate
KW - Membrane permeability
KW - Rat serum
KW - Sodium
KW - Taurocholate
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U2 - 10.1016/S1383-5866(03)00007-8
DO - 10.1016/S1383-5866(03)00007-8
M3 - Article
AN - SCOPUS:0141849254
SN - 1383-5866
VL - 33
SP - 189
EP - 197
JO - Gas Separation and Purification
JF - Gas Separation and Purification
IS - 2
ER -