Respiratory syncytial virus (RSV) is a major causative agent of respiratory infection in infants because of its affinity for bronchial and alveolar epithelial cells. Serious and sometimes fatal RSV infection may develop in premature infants as well as infants with chronic lung disease and congenital heart disease (CHD). In infants with CHD, the addition of RSV infection to the underlying respiratory pathology resulting from increase or decrease in pulmonary blood flow may cause significant problems such as serious symptoms, increases in hospitalization rate, postponement of elective heart surgery, or death. Strict infection control measures with administration of anti-RSV antibody are essential in the management of infants with heart and lung diseases.
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