Reticuloendothelial System-Potentiating and Alkaline Phosphatase-Inducing Activities of Plantago-Mucilage A, the Main Mucilage from the Seed of Plantago asiatica, and Its Five Modification Products

Masashi Tomoda, Katsutoshi Takada, Noriko Shimizu, Ryoko Gonda, Naoko Ohara

研究成果: Article査読

10 被引用数 (Scopus)

抄録

Five kinds of chemically modified products were prepared from Plantago-mucilage A, the representative mucous polysaccharide isolated from the seed of Plantago asiatica L., and their reticuloendothelial system-potentiating and alkaline phosphatase-inducing activities have been investigated. Both activities were markedly enhanced when the mucilage was de-O-acetylated. The products obtained by periodate oxidation, controlled Smith degradation, and partial acid hydrolysis under the two conditions were not effective. Structural features of the partial hydrolyzates were elucidated, and it was shown that these products lost all 0-acetyl groups, all xylose branches and many hexuronosyl arabinose side chains.

本文言語English
ページ(範囲)2068-2071
ページ数4
ジャーナルChemical and Pharmaceutical Bulletin
39
8
DOI
出版ステータスPublished - 1991

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

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