抄録
Biological agents targeting a specific molecule have extraordinarily fine specificity and powerful functional capabilities. By the introduction of biological therapy, management of rheumatoid arthritis has undergone a revolution and a paradigm shift. In this review, I will summarize the role in the pathogenesis of rheumatoid arthritis of the molecules targeted by biological agents. Providing evidence obtained in clinical trials and investigator-initiated clinical studies in Japan, the effectiveness and safety of biological therapy in rheumatoid arthritis are discussed. Finally, studies aiming at a personalized strategy with biological agents are listed and the future perspectives toward tailor-made medicine in the field of rheumatology are discussed.
本文言語 | English |
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ページ(範囲) | 75-81 |
ページ数 | 7 |
ジャーナル | Keio Journal of Medicine |
巻 | 60 |
号 | 3 |
DOI | |
出版ステータス | Published - 2011 6月 |
外部発表 | はい |
ASJC Scopus subject areas
- 医学(全般)