Revolutionary change in rheumatoid arthritis management with biological therapy

研究成果: Review article査読

21 被引用数 (Scopus)

抄録

Biological agents targeting a specific molecule have extraordinarily fine specificity and powerful functional capabilities. By the introduction of biological therapy, management of rheumatoid arthritis has undergone a revolution and a paradigm shift. In this review, I will summarize the role in the pathogenesis of rheumatoid arthritis of the molecules targeted by biological agents. Providing evidence obtained in clinical trials and investigator-initiated clinical studies in Japan, the effectiveness and safety of biological therapy in rheumatoid arthritis are discussed. Finally, studies aiming at a personalized strategy with biological agents are listed and the future perspectives toward tailor-made medicine in the field of rheumatology are discussed.

本文言語English
ページ(範囲)75-81
ページ数7
ジャーナルKeio Journal of Medicine
60
3
DOI
出版ステータスPublished - 2011 6
外部発表はい

ASJC Scopus subject areas

  • 医学(全般)

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