Rheumatoid neutrophilic dermatosis with tense blister formation: A case report and review of the literature

Yumi Fujio, Takeru Funakoshi, Kaori Nakayama, Masayuki Amagai, Manabu Ohyama

研究成果: Article

5 引用 (Scopus)

抄録

We report a 78-year-old woman with rheumatoid neutrophilic dermatosis (RND) presenting with tense blisters; an extremely rare manifestation of this condition. Systemic corticosteroid was of limited efficacy, while dapsone was effective. A literature review of four similar cases showed that tense blisters in this type of RND tended to appear on the lower extremities of aged, female rheumatoid arthritis patients. Of note, half of the cases were resistant to corticosteroids, as anti-neutrophil agents are reported to be effective. Accordingly, it is important to recognise this unusual manifestation for the timely initiation of appropriate therapy.

元の言語English
ジャーナルAustralasian Journal of Dermatology
55
発行部数1
DOI
出版物ステータスPublished - 2014 2

Fingerprint

Blister
Skin Diseases
Adrenal Cortex Hormones
Dapsone
Lower Extremity
Rheumatoid Arthritis
Neutrophils
Therapeutics

ASJC Scopus subject areas

  • Dermatology
  • Medicine(all)

これを引用

@article{3eb2eae128f3430799f12d652857d048,
title = "Rheumatoid neutrophilic dermatosis with tense blister formation: A case report and review of the literature",
abstract = "We report a 78-year-old woman with rheumatoid neutrophilic dermatosis (RND) presenting with tense blisters; an extremely rare manifestation of this condition. Systemic corticosteroid was of limited efficacy, while dapsone was effective. A literature review of four similar cases showed that tense blisters in this type of RND tended to appear on the lower extremities of aged, female rheumatoid arthritis patients. Of note, half of the cases were resistant to corticosteroids, as anti-neutrophil agents are reported to be effective. Accordingly, it is important to recognise this unusual manifestation for the timely initiation of appropriate therapy.",
keywords = "blister formation, bullous pemphigoid, neutrophilic dermatosis, rheumatoid arthritis",
author = "Yumi Fujio and Takeru Funakoshi and Kaori Nakayama and Masayuki Amagai and Manabu Ohyama",
year = "2014",
month = "2",
doi = "10.1111/j.1440-0960.2012.00963.x",
language = "English",
volume = "55",
journal = "Australasian Journal of Dermatology",
issn = "0004-8380",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Rheumatoid neutrophilic dermatosis with tense blister formation

T2 - A case report and review of the literature

AU - Fujio, Yumi

AU - Funakoshi, Takeru

AU - Nakayama, Kaori

AU - Amagai, Masayuki

AU - Ohyama, Manabu

PY - 2014/2

Y1 - 2014/2

N2 - We report a 78-year-old woman with rheumatoid neutrophilic dermatosis (RND) presenting with tense blisters; an extremely rare manifestation of this condition. Systemic corticosteroid was of limited efficacy, while dapsone was effective. A literature review of four similar cases showed that tense blisters in this type of RND tended to appear on the lower extremities of aged, female rheumatoid arthritis patients. Of note, half of the cases were resistant to corticosteroids, as anti-neutrophil agents are reported to be effective. Accordingly, it is important to recognise this unusual manifestation for the timely initiation of appropriate therapy.

AB - We report a 78-year-old woman with rheumatoid neutrophilic dermatosis (RND) presenting with tense blisters; an extremely rare manifestation of this condition. Systemic corticosteroid was of limited efficacy, while dapsone was effective. A literature review of four similar cases showed that tense blisters in this type of RND tended to appear on the lower extremities of aged, female rheumatoid arthritis patients. Of note, half of the cases were resistant to corticosteroids, as anti-neutrophil agents are reported to be effective. Accordingly, it is important to recognise this unusual manifestation for the timely initiation of appropriate therapy.

KW - blister formation

KW - bullous pemphigoid

KW - neutrophilic dermatosis

KW - rheumatoid arthritis

UR - http://www.scopus.com/inward/record.url?scp=84892830817&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892830817&partnerID=8YFLogxK

U2 - 10.1111/j.1440-0960.2012.00963.x

DO - 10.1111/j.1440-0960.2012.00963.x

M3 - Article

C2 - 23094684

AN - SCOPUS:84892830817

VL - 55

JO - Australasian Journal of Dermatology

JF - Australasian Journal of Dermatology

SN - 0004-8380

IS - 1

ER -