RHO gene products, putative small GTP‐binding proteins, are importnat for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae

Hiroshi Qadota, Isao Ishii, Asao Fujiyama, Yoshikazu Ohya, Yasuhiro Anraku

研究成果: Article査読

53 被引用数 (Scopus)

抄録

Two multicopy suppressors of the call‐1 mutation in the yeast Saccharomyces cerevisiae have been isolated and characterized. They are identical to the yeast RHO1 and RHO2 genes, which encode putative small GTP‐binding proteins. Multiple copies of either RHO gene suppressed temperature‐sensitive growth of the call‐1 mutant but did not suppress the call null mutant. Genetic analysis suggests that overproduction of either RHO gene product acts for activation of the CAL1 gene product.

本文言語English
ページ(範囲)735-741
ページ数7
ジャーナルYeast
8
9
DOI
出版ステータスPublished - 1992 9月

ASJC Scopus subject areas

  • バイオテクノロジー
  • バイオエンジニアリング
  • 生化学
  • 応用微生物学とバイオテクノロジー
  • 遺伝学

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