Riociguat, a soluble guanylate cyclase stimulator, ameliorates right ventricular contraction in pulmonary arterial hypertension

Mitsushige Murata, Takashi Kawakami, Masaharu Kataoka, Takashi Kohno, Yuji Itabashi, Keiichi Fukuda

研究成果: Letter

4 引用 (Scopus)

抄録

Riociguat is a soluble guanylate cyclase stimulator used for pulmonary hypertension (PH) treatment. We evaluated right ventricular (RV) contractile function in 27 PH patients receiving riociguat. A comparison of pre- and post-administration echocardiographic studies demonstrated significantly improved RV strain after riociguat treatment, even after adjusting for RV afterload.

元の言語English
ジャーナルPulmonary Circulation
8
発行部数1
DOI
出版物ステータスPublished - 2018 1 1

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Pulmonary Hypertension
Right Ventricular Function
Therapeutics
riociguat
Soluble Guanylyl Cyclase

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

これを引用

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abstract = "Riociguat is a soluble guanylate cyclase stimulator used for pulmonary hypertension (PH) treatment. We evaluated right ventricular (RV) contractile function in 27 PH patients receiving riociguat. A comparison of pre- and post-administration echocardiographic studies demonstrated significantly improved RV strain after riociguat treatment, even after adjusting for RV afterload.",
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AU - Murata, Mitsushige

AU - Kawakami, Takashi

AU - Kataoka, Masaharu

AU - Kohno, Takashi

AU - Itabashi, Yuji

AU - Fukuda, Keiichi

PY - 2018/1/1

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KW - Pulmonary hypertension

KW - Right ventricular contraction

KW - Riociguat

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