Role of Na+-Ca2+ exchange in neonatal and adult ventricular cells: A simulation study

Hitomi I. Sano, Yasuhiro Naito, Masaru Tomita

研究成果: Conference contribution

抜粋

The Na+-Ca2+ exchange assumes considerable importance in neonatal cells with a morphologically sparse sarcoplasmic reticulum. Our simulation shows that the neonatal ventricular cell consumed larger amount of ATP than the adult ventricular cell, owing to a long relaxation time. The amount of ATP consumed per beat was reduced to the amount equivalent to the adult ventricular cells, thus increasing the relative current density of Na +-Ca2+ exchange by 4-fold, which is consistent with the observed current density in the neonatal rabbit ventricular cells.

元の言語English
ホスト出版物のタイトルComputing in Cardiology 2012, CinC 2012
ページ877-880
ページ数4
出版物ステータスPublished - 2012 12 1
イベント39th Computing in Cardiology Conference, CinC 2012 - Krakow, Poland
継続期間: 2012 9 92012 9 12

出版物シリーズ

名前Computing in Cardiology
39
ISSN(印刷物)2325-8861
ISSN(電子版)2325-887X

Other

Other39th Computing in Cardiology Conference, CinC 2012
Poland
Krakow
期間12/9/912/9/12

ASJC Scopus subject areas

  • Computer Science(all)
  • Cardiology and Cardiovascular Medicine

フィンガープリント Role of Na<sup>+</sup>-Ca<sup>2+</sup> exchange in neonatal and adult ventricular cells: A simulation study' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Sano, H. I., Naito, Y., & Tomita, M. (2012). Role of Na+-Ca2+ exchange in neonatal and adult ventricular cells: A simulation study. : Computing in Cardiology 2012, CinC 2012 (pp. 877-880). [6420534] (Computing in Cardiology; 巻数 39).