Role of reelin during layer formation in the cerebralneocortex

研究成果: Review article査読

抄録

Reelin controls the neuronal layer formation in the developing cerebral neocortex. The Reelin glycoprotein is mainly secreted from Cajat-Retzius cells in the marginal zone, and it guides the proper aggregation of the migrating neurons in a birth-dependent "inside-out" manner. Reelin also regulates the final process of neuronal migration (terminal translocation and somal translocation) by activating integrin and N-cadherin. It is also expressed around the subventricular zone and it controls the behavior of the migrating neurons.

本文言語English
ページ(範囲)931-937
ページ数7
ジャーナルBrain and Nerve
68
8
出版ステータスPublished - 2016 8

ASJC Scopus subject areas

  • Clinical Neurology

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