TY - JOUR
T1 - Roles of oxidative stress in stomach disorders
AU - Suzuki, Hidekazu
AU - Nishizawa, Toshihiro
AU - Tsugawa, Hitoshi
AU - Mogami, Sachiko
AU - Hibi, Toshifumi
PY - 2012
Y1 - 2012
N2 - The stomach is a sensitive digestive organ that is susceptible and exposed to exogenous pathogens from the diet. In response to such pathogens, the stomach induces oxidative stress, which might be related to the development of gastric organic disorders such as gastritis, gastric ulcers, and gastric cancer, as well as functional disorders such as functional dyspepsia. In particular, the bacterium Helicobacter pylori plays a major role in eliciting and confronting oxidative stress in the stomach. The present paper summarizes the pathogenesis of oxidative stress in the stomach during the development of various stomach diseases.
AB - The stomach is a sensitive digestive organ that is susceptible and exposed to exogenous pathogens from the diet. In response to such pathogens, the stomach induces oxidative stress, which might be related to the development of gastric organic disorders such as gastritis, gastric ulcers, and gastric cancer, as well as functional disorders such as functional dyspepsia. In particular, the bacterium Helicobacter pylori plays a major role in eliciting and confronting oxidative stress in the stomach. The present paper summarizes the pathogenesis of oxidative stress in the stomach during the development of various stomach diseases.
KW - Gastric mucosa
KW - Helicobacter pylori
KW - Oxidative stress
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U2 - 10.3164/jcbn.11-115SR
DO - 10.3164/jcbn.11-115SR
M3 - Review article
C2 - 22247598
AN - SCOPUS:84855393983
VL - 50
SP - 35
EP - 39
JO - Journal of Clinical Biochemistry and Nutrition
JF - Journal of Clinical Biochemistry and Nutrition
SN - 0912-0009
IS - 1
ER -
