Roles of stem cell antigen-1 in the pulmonary endothelium

Jun Maeda, Keiko Uchida, Kazuki Kodo, Hiroyuki Yamagishi

研究成果: Chapter

抄録

There is growing evidence that resident progenitor cell populations exist in murine lung tissues and differentiate into a mesenchymal cell lineage [1, 2]. Stem cell antigen-1 (Sca-1) is a cell surface glycoprotein, initially found in murine bone marrow-derived stem cell subtypes, such as hematopoietic stem cells. Some studies showed Sca-1 expression in the pulmonary vascular endothelium of adult murine lungs [3], while a subset of Sca-1-expressing cells formed vascular-like structures under specific conditions [1].

本文言語English
ホスト出版物のタイトルMolecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension
出版社Springer Singapore
ページ87-89
ページ数3
ISBN(電子版)9789811511851
ISBN(印刷版)9789811511844
DOI
出版ステータスPublished - 2020 1月 1

ASJC Scopus subject areas

  • 医学(全般)

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