Ruthenium-Catalyzed Ortho C-H Arylation of Aromatic Nitriles with Arylboronates and Observation of Partial Para Arylation

Yuta Koseki, Kentaroh Kitazawa, Masashi Miyake, Takuya Kochi, Fumitoshi Kakiuchi

研究成果: Article査読

16 被引用数 (Scopus)

抄録

Ruthenium-catalyzed C-H arylation of aromatic nitriles with arylboronates is described. The use of RuH2(CO){P(4-MeC6H4)3}3 as a catalyst provided higher yields of the ortho arylation products than the conventional RuH2(CO)(PPh3)3 catalyst. The arylation takes place mostly at the ortho positions, but unprecedented para arylation was also partially observed to give ortho,para diarylation products. In addition to C-H bond cleavage, the cyano group was also found to function as a directing group for cleavage of C-O bonds in aryl ethers.

本文言語English
ページ(範囲)6503-6510
ページ数8
ジャーナルJournal of Organic Chemistry
82
13
DOI
出版ステータスPublished - 2017 7 7

ASJC Scopus subject areas

  • 有機化学

フィンガープリント

「Ruthenium-Catalyzed Ortho C-H Arylation of Aromatic Nitriles with Arylboronates and Observation of Partial Para Arylation」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル