Ruthenium(II)-catalyzed regio- and stereoselective hydroarylation of alkynes via directed C-H functionalization

Yuto Hashimoto, Koji Hirano, Tetsuya Satoh, Fumitoshi Kakiuchi, Masahiro Miura

研究成果: Article査読

122 被引用数 (Scopus)

抄録

The ruthenium-catalyzed hydroarylation of alkynes with benzamides proceeds regio- and stereoselectively through a directed C-H bond cleavage. Preliminary mechanistic investigations indicate that the reaction involves amide-directed ortho-metalation, carbometalation of alkyne, and protonolysis. Similarly, phenylazoles also add to alkynes regioselectively.

本文言語English
ページ(範囲)2058-2061
ページ数4
ジャーナルOrganic Letters
14
8
DOI
出版ステータスPublished - 2012 4 20

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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