Safety and efficacy of plasma exchange via direct femoral vein puncture in autoimmune blistering diseases

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Plasma exchange (PE) is performed for patients with autoimmune blistering diseases by using multiple vascular access routes. We retrospectively examined the safety and the efficacy of PE using direct femoral vein puncture (FVP) technique, by comparing with that using double-lumen catheter (DLC). The troubles related to vascular route, such as catheter occlusion, insufficient blood flow and hematoma, were not different between the FVP group (4.6%) and the DLC group (6.7%), whereas access-related infections occurred more frequently in the DLC group (6.7%) than the FVP group (0.4%). Regarding the efficacy, the removal rate of autoantibodies in PE using the FVP technique was similar or lower, as compared with that using the DLC. These results suggest that PE with the FVP technique is able to be performed safely in patients with autoimmune blistering diseases, although the removal of autoantibodies is not superior to that using the DLC.

本文言語English
ページ(範囲)172-177
ページ数6
ジャーナルJournal of Clinical Apheresis
35
3
DOI
出版ステータスPublished - 2020 6 1

ASJC Scopus subject areas

  • 血液学

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