Safety of biologic agents in elderly patients with rheumatoid arthritis

Atsuko Murota, Yuko Kaneko, Kunihiro Yamaoka, Tsutomu Takeuchi

研究成果: Article

10 引用 (Scopus)

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Objective. To clarify the safety of biologics in elderly patients with rheumatoid arthritis. Methods. Biologics were analyzed for safety in relation to age in 309 patients. Results. Young (< 65 yrs old, n = 174), elderly (65-74 yrs old, n = 86), and older elderly patients (? 75 yrs old, n = 49) were enrolled. Although the incidence of adverse events causing treatment withdrawal was significantly higher in elderly and old elderly compared with young patients, no difference was found between elderly and older elderly patients. Pulmonary complications were independent risk factors. Conclusion. Old patients require special attention, although the safety of biologics in those ? 75 years old and 65-74 was comparable.

元の言語English
ページ(範囲)1984-1988
ページ数5
ジャーナルJournal of Rheumatology
43
発行部数11
DOI
出版物ステータスPublished - 2016 11 1

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology

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