Scientific advances in lung cancer 2015

Anne S. Tsao, Giorgio V. Scagliotti, Paul A. Bunn, David P. Carbone, Graham W. Warren, Chunxue Bai, Harry J. De Koning, A. Uraujh Yousaf-Khan, Annette McWilliams, Ming Sound Tsao, Prasad S. Adusumilli, Ramón Rami-Porta, Hisao Asamura, Paul E. Van Schil, Gail E. Darling, Suresh S. Ramalingam, Daniel R. Gomez, Kenneth E. Rosenzweig, Stefan Zimmermann, Solange PetersSai Hong Ignatius Ou, Thanyanan Reungwetwattana, Pasi A. Jänne, Tony S. Mok, Heather A. Wakelee, Robert Pirker, Julien Mazières, Julie R. Brahmer, Yang Zhou, Roy S. Herbst, Vassiliki A. Papadimitrakopoulou, Mary W. Redman, Murry W. Wynes, David R. Gandara, Ronan J. Kelly, Fred R. Hirsch, Harvey I. Pass

研究成果: Review article査読

136 被引用数 (Scopus)

抄録

Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a "role model" for precision cancer medicine, with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogene-driven tumors and about resistance to targeted therapies has increased quickly over the past year. As a result, several regulatory approvals of new agents that significantly improve survival and quality of life for patients with lung cancer who have advanced disease have occurred. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the past year.

本文言語English
ページ(範囲)613-638
ページ数26
ジャーナルJournal of Thoracic Oncology
11
5
DOI
出版ステータスPublished - 2016

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

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