Screening of crude drugs used in Nepal for nematocidal activity on the larva of toxocara canis

F. Kiuchi, M. Hayashi, N. Nakamura, M. Mikage, Y. Tsuda, K. Kondo, T. Namba

研究成果: Article査読

4 被引用数 (Scopus)

抄録

Hot water extracts of 160 crude drugs used in Nepal were tested for their in vitro nematocidal activity on the second-stage larva of the dog roundworm, Toxocara cains, which is a common pathogenic parasite in larva migrans. Twenty-two of them showed a potent nematocidal activity (RM = 0, after 24 h incubation), and the activities of ''Bojho'' (rhizome of Acorus calamus L.) and ''Pan ko Jara'' (rhizome of Alpinia galanga SWARTZ) were particularly strong (RM = 0, after 6 h incubation). The active principle of Pan ko Jara was identified as [S]-1'-acetoxychavicol acetate.

本文言語English
ページ(範囲)294-299
ページ数6
ジャーナルJapanese Journal of Pharmacognosy
43
4
出版ステータスPublished - 1989
外部発表はい

ASJC Scopus subject areas

  • 分子医療
  • 薬理学

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