Search for a susceptibility locus to tardive dyskinesia

Toshiya Inada, Izumi Dobashi, Tetsuyoshi Sugita, Ataru Inagaki, Yoshie Kitao, Genichi Matsuda, Shingo Kato, Toshiya Takano, Gohei Yagi, Masahiro Asai

研究成果: Article

32 引用 (Scopus)

抜粋

In order to find a genetic marker for vulnerability to tardive dyskinesia (TD), we looked for an association between vulnerability to TD and polymorphic sites in the gene loci encoding the dopamine D2 receptor (Nco I site), the dopamine D3 receptor (Bal I site), and the dopamine transporter (40-bp, tandem repeat polymorphism). No significant difference was observed in the allele and genotype frequencies of any of the polymorphic sites examined, when comparing psychiatric patients who were specifically vulnerable to TD (n = 49) and those who were not (n = 56). These results suggest that the polymorphic gene loci examined in the present study are unlikely to be of major aetiologic importance in the development of TD.

元の言語English
ページ(範囲)35-39
ページ数5
ジャーナルHuman Psychopharmacology
12
発行部数1
DOI
出版物ステータスPublished - 1997 1 1

    フィンガープリント

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Pharmacology (medical)

これを引用

Inada, T., Dobashi, I., Sugita, T., Inagaki, A., Kitao, Y., Matsuda, G., Kato, S., Takano, T., Yagi, G., & Asai, M. (1997). Search for a susceptibility locus to tardive dyskinesia. Human Psychopharmacology, 12(1), 35-39. https://doi.org/10.1002/(sici)1099-1077(199701/02)12:1<35::aid-hup828>3.0.co;2-%23