Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer

Shigenari Nukaga; Katsuhiko Naoki; Hiroyuki Yasuda; Ichiro Kawada; Kentaro Ohara; Kenzo Soejima; Tomoko Betsuyaku

doi:10.2169/internalmedicine.0184-17

Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer

Shigenari Nukaga, Katsuhiko Naoki, Hiroyuki Yasuda, Ichiro Kawada, Kentaro Ohara, Kenzo Soejima, Tomoko Betsuyaku

研究成果: Article

抜粋

Stereotactic radiosurgery (SRS) using the Gamma Knife (GK) is now being increasingly utilized for the treatment of brain metastases. However, there are a few reported cases of SRS-induced brain neoplasms. We herein report the case of a Japanese woman with metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor (EGFR)-mutations who was treated four times with a GK for brain metastases. She developed glioblastoma 5.7 years after the initial GK surgery. Radiation-induced secondary neoplasms generally appear after a latency period of several years. Advances in cancer therapy have improved the survival of patients with NSCLC, providing enough time for secondary neoplasms to appear after SRS.

元の言語	English
ページ（範囲）	2383-2387
ページ数	5
ジャーナル	Internal Medicine
巻	57
発行部数	16
DOI	https://doi.org/10.2169/internalmedicine.0184-17
出版物ステータス	Published - 2018 1 1

ASJC Scopus subject areas

Internal Medicine

文献にアクセス

10.2169/internalmedicine.0184-17

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これを引用

Nukaga, S., Naoki, K., Yasuda, H., Kawada, I., Ohara, K., Soejima, K., & Betsuyaku, T. (2018). Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer. Internal Medicine, 57(16), 2383-2387. https://doi.org/10.2169/internalmedicine.0184-17

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AU - Ohara, Kentaro

AU - Soejima, Kenzo

AU - Betsuyaku, Tomoko

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