Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer

Shigenari Nukaga, Katsuhiko Naoki, Hiroyuki Yasuda, Ichiro Kawada, Kentaro Ohara, Kenzo Soejima, Tomoko Betsuyaku

研究成果: Article

抄録

Stereotactic radiosurgery (SRS) using the Gamma Knife (GK) is now being increasingly utilized for the treatment of brain metastases. However, there are a few reported cases of SRS-induced brain neoplasms. We herein report the case of a Japanese woman with metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor (EGFR)-mutations who was treated four times with a GK for brain metastases. She developed glioblastoma 5.7 years after the initial GK surgery. Radiation-induced secondary neoplasms generally appear after a latency period of several years. Advances in cancer therapy have improved the survival of patients with NSCLC, providing enough time for secondary neoplasms to appear after SRS.

元の言語English
ページ(範囲)2383-2387
ページ数5
ジャーナルInternal Medicine
57
発行部数16
DOI
出版物ステータスPublished - 2018 1 1

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Radiosurgery
Non-Small Cell Lung Carcinoma
Brain Neoplasms
Radiation-Induced Neoplasms
Neoplasm Metastasis
Brain
Glioblastoma
Epidermal Growth Factor
Neoplasms
Mutation
Survival
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

これを引用

Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer. / Nukaga, Shigenari; Naoki, Katsuhiko; Yasuda, Hiroyuki; Kawada, Ichiro; Ohara, Kentaro; Soejima, Kenzo; Betsuyaku, Tomoko.

:: Internal Medicine, 巻 57, 番号 16, 01.01.2018, p. 2383-2387.

研究成果: Article

Nukaga, Shigenari ; Naoki, Katsuhiko ; Yasuda, Hiroyuki ; Kawada, Ichiro ; Ohara, Kentaro ; Soejima, Kenzo ; Betsuyaku, Tomoko. / Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer. :: Internal Medicine. 2018 ; 巻 57, 番号 16. pp. 2383-2387.
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AU - Betsuyaku, Tomoko

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