抄録
Stereotactic radiosurgery (SRS) using the Gamma Knife (GK) is now being increasingly utilized for the treatment of brain metastases. However, there are a few reported cases of SRS-induced brain neoplasms. We herein report the case of a Japanese woman with metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor (EGFR)-mutations who was treated four times with a GK for brain metastases. She developed glioblastoma 5.7 years after the initial GK surgery. Radiation-induced secondary neoplasms generally appear after a latency period of several years. Advances in cancer therapy have improved the survival of patients with NSCLC, providing enough time for secondary neoplasms to appear after SRS.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 2383-2387 |
| ページ数 | 5 |
| ジャーナル | Internal Medicine |
| 巻 | 57 |
| 発行部数 | 16 |
| DOI | |
| 出版物ステータス | Published - 2018 1 1 |
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ASJC Scopus subject areas
- Internal Medicine
これを引用
Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer. / Nukaga, Shigenari; Naoki, Katsuhiko; Yasuda, Hiroyuki; Kawada, Ichiro; Ohara, Kentaro; Soejima, Kenzo; Betsuyaku, Tomoko.
：: Internal Medicine, 巻 57, 番号 16, 01.01.2018, p. 2383-2387.研究成果: Article
}
TY - JOUR
T1 - Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer
AU - Nukaga, Shigenari
AU - Naoki, Katsuhiko
AU - Yasuda, Hiroyuki
AU - Kawada, Ichiro
AU - Ohara, Kentaro
AU - Soejima, Kenzo
AU - Betsuyaku, Tomoko
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Stereotactic radiosurgery (SRS) using the Gamma Knife (GK) is now being increasingly utilized for the treatment of brain metastases. However, there are a few reported cases of SRS-induced brain neoplasms. We herein report the case of a Japanese woman with metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor (EGFR)-mutations who was treated four times with a GK for brain metastases. She developed glioblastoma 5.7 years after the initial GK surgery. Radiation-induced secondary neoplasms generally appear after a latency period of several years. Advances in cancer therapy have improved the survival of patients with NSCLC, providing enough time for secondary neoplasms to appear after SRS.
AB - Stereotactic radiosurgery (SRS) using the Gamma Knife (GK) is now being increasingly utilized for the treatment of brain metastases. However, there are a few reported cases of SRS-induced brain neoplasms. We herein report the case of a Japanese woman with metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor (EGFR)-mutations who was treated four times with a GK for brain metastases. She developed glioblastoma 5.7 years after the initial GK surgery. Radiation-induced secondary neoplasms generally appear after a latency period of several years. Advances in cancer therapy have improved the survival of patients with NSCLC, providing enough time for secondary neoplasms to appear after SRS.
KW - Brain metastases
KW - Non-small cell lung cancer
KW - Radiosurgery induced brain neoplasm
KW - Stereotactic radiosurgery
UR - http://www.scopus.com/inward/record.url?scp=85051708295&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85051708295&partnerID=8YFLogxK
U2 - 10.2169/internalmedicine.0184-17
DO - 10.2169/internalmedicine.0184-17
M3 - Article
C2 - 29526937
AN - SCOPUS:85051708295
VL - 57
SP - 2383
EP - 2387
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 16
ER -