Secondary brain neoplasm after stereotactic radiosurgery in patients with metastatic non-small cell lung cancer

Shigenari Nukaga, Katsuhiko Naoki, Hiroyuki Yasuda, Ichiro Kawada, Kentaro Ohara, Kenzo Soejima, Tomoko Betsuyaku

研究成果: Article

抜粋

Stereotactic radiosurgery (SRS) using the Gamma Knife (GK) is now being increasingly utilized for the treatment of brain metastases. However, there are a few reported cases of SRS-induced brain neoplasms. We herein report the case of a Japanese woman with metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor (EGFR)-mutations who was treated four times with a GK for brain metastases. She developed glioblastoma 5.7 years after the initial GK surgery. Radiation-induced secondary neoplasms generally appear after a latency period of several years. Advances in cancer therapy have improved the survival of patients with NSCLC, providing enough time for secondary neoplasms to appear after SRS.

元の言語English
ページ(範囲)2383-2387
ページ数5
ジャーナルInternal Medicine
57
発行部数16
DOI
出版物ステータスPublished - 2018 1 1

ASJC Scopus subject areas

  • Internal Medicine

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