Self-organized 3D bridging of cardiomyocytes toward creation of ultra small cell-driven pumps integrated in microstructure

Y. Tanaka, T. Yamashita, V. Vogel

研究成果: Conference contribution

抄録

We investigated the self-organized bridging phenomenon of cardiomyocytes in microgroove structure. Cardiomyocytes formed several bridges inside the microgrooves. The bridging tissues were completely apart from the bottom of microgroove, and surprisingly, the both edges were connecting to the micro-groove walls at middle heights. Bridging of cardiomyocytes was most observed when the groove aspect ratio is around 1 regardless of the depth of the microgrooves, suggesting that cell-generated force has a major role in bridge formation. Our semi-quantitative observation gives an insight to the self tissue organization process in microstructures and would be useful criterion to design ultra small bio-micropumps.

本文言語English
ホスト出版物のタイトルMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Chemical and Biological Microsystems Society
ページ1773-1775
ページ数3
ISBN(電子版)9780979806483
出版ステータスPublished - 2015
外部発表はい
イベント19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
継続期間: 2015 10月 252015 10月 29

出版物シリーズ

名前MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
国/地域Korea, Republic of
CityGyeongju
Period15/10/2515/10/29

ASJC Scopus subject areas

  • 制御およびシステム工学

フィンガープリント

「Self-organized 3D bridging of cardiomyocytes toward creation of ultra small cell-driven pumps integrated in microstructure」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル