Severe cerebral and systemic necrotizing vasculitis developing during pregnancy in a case of systemic lupus erythematosus

Y. Suzuki, Y. Kitagawa, Y. Matsuoka, J. Fukuda, Y. Mizushima

研究成果: Article査読

17 被引用数 (Scopus)

抄録

We describe a fatal case of systemic lupus erythematosus (SLE) developing cerebral and systemic necrotizing vasculitis during pregnancy. The patient was discovered to have SLE at 14 weeks' gestation. Although the symptoms disappeared without treatment with corticosteroid in the 2nd trimester, she presented with meningoencephalitis due to vasculitis in the 3rd trimester. Polyarteritis nodosa (PAN)-like necrotizing vasculitis of the small muscular arteries and arterioles, with acute and healing lesions in the leptomeninges, brain parenchyma and visceral organs was observed at postpartum autopsy. PAN-like vasculitis in the central nervous system is quite rare in SLE. This case is also suggestive in terms of the influence of pregnancy on the activity of SLE.

本文言語English
ページ(範囲)1408-1411
ページ数4
ジャーナルJournal of Rheumatology
17
10
出版ステータスPublished - 1990
外部発表はい

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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