Shear-induced structural transitions of peptide amphiphile

Atsushi Hotta, Tomoko Shimada, Matthew Tirrell

研究成果: Conference contribution

抄録

A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo "hierarchical multi-scale structural transitions" ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).

元の言語English
ホスト出版物のタイトルPolymer Preprints, Japan
ページ3933-3934
ページ数2
55
エディション2
出版物ステータスPublished - 2006
イベント55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
継続期間: 2006 9 202006 9 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
Japan
Toyama
期間06/9/2006/9/22

Fingerprint

Amphiphiles
Peptides
Dynamic mechanical analysis
Gelation
Micelles
Cryogenics
Macros
Viscosity
Transmission electron microscopy
Fibers

ASJC Scopus subject areas

  • Engineering(all)

これを引用

Hotta, A., Shimada, T., & Tirrell, M. (2006). Shear-induced structural transitions of peptide amphiphile. : Polymer Preprints, Japan (2 版, 巻 55, pp. 3933-3934)

Shear-induced structural transitions of peptide amphiphile. / Hotta, Atsushi; Shimada, Tomoko; Tirrell, Matthew.

Polymer Preprints, Japan. 巻 55 2. 編 2006. p. 3933-3934.

研究成果: Conference contribution

Hotta, A, Shimada, T & Tirrell, M 2006, Shear-induced structural transitions of peptide amphiphile. : Polymer Preprints, Japan. 2 Edn, 巻. 55, pp. 3933-3934, 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan, 06/9/20.
Hotta A, Shimada T, Tirrell M. Shear-induced structural transitions of peptide amphiphile. : Polymer Preprints, Japan. 2 版 巻 55. 2006. p. 3933-3934
Hotta, Atsushi ; Shimada, Tomoko ; Tirrell, Matthew. / Shear-induced structural transitions of peptide amphiphile. Polymer Preprints, Japan. 巻 55 2. 版 2006. pp. 3933-3934
@inproceedings{127199427f1a4e9fa445698da4b1afe2,
title = "Shear-induced structural transitions of peptide amphiphile",
abstract = "A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo {"}hierarchical multi-scale structural transitions{"} ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).",
keywords = "Hierarchical structural transitions, Peptide amphiphiles",
author = "Atsushi Hotta and Tomoko Shimada and Matthew Tirrell",
year = "2006",
language = "English",
volume = "55",
pages = "3933--3934",
booktitle = "Polymer Preprints, Japan",
edition = "2",

}

TY - GEN

T1 - Shear-induced structural transitions of peptide amphiphile

AU - Hotta, Atsushi

AU - Shimada, Tomoko

AU - Tirrell, Matthew

PY - 2006

Y1 - 2006

N2 - A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo "hierarchical multi-scale structural transitions" ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).

AB - A novel method to construct hierarchical supramolecular structures in the designed peptide amphiphile solution was introduced. By simply shaking the solution at a certain frequency, the viscosity of the solution dramatically increased due to the conformational transitions and the construction of worm-like micelles, eventually causing networking of the nano-fibers made of peptide amphiphiles. The result implies that the new peptide amphiphiles undergo "hierarchical multi-scale structural transitions" ranging from a molecular-scale conformational transition, through nano-scale fibril formations, to macro-scale gelation, all caused by mechanical shear at a certain frequency. The transition was measured by Dynamic Mechanical Analysis (DMA), Circular Dichroism (CD) and cryogenic Transmission Electron Microscopy (cryo-TEM).

KW - Hierarchical structural transitions

KW - Peptide amphiphiles

UR - http://www.scopus.com/inward/record.url?scp=33846162295&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846162295&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:33846162295

VL - 55

SP - 3933

EP - 3934

BT - Polymer Preprints, Japan

ER -