Silver-catalyzed three-component reaction of propargylic amines, carbon dioxide, and N-iodosuccinimide for stereoselective preparation of (E)-iodovinyloxazolidinones

Kohei Sekine, Ryo Kobayashi, Tohru Yamada

研究成果: Article査読

34 被引用数 (Scopus)

抄録

The silver-catalyzed three-component reaction of propargylic amines, carbon dioxide, and N-iodosuccinimide for the stereoselective synthesis of (E)-iodovinyloxazolidinones was developed. The silver-catalytic system could be applied to various propargylic amines to afford the corresponding iodovinyloxazolidinones in high yields. The structure of the oxazolidinone was confirmed by X-ray structure analysis to be the Eisomer for the geometry of the exo-olefin. The silver-catalyzed cyclization and replacement of silver with the iodine group in the intermediate were thought to be crucial steps.

本文言語English
ページ(範囲)1407-1409
ページ数3
ジャーナルChemistry Letters
44
10
DOI
出版ステータスPublished - 2015

ASJC Scopus subject areas

  • 化学 (全般)

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