抄録
C-C bond-forming carboxylation and cyclization of trimethyl(2-methylenebut-3-yn-1-yl)silane derivatives and carbon dioxide was developed. Silver catalysts and CsF promoted the reaction to afford the corresponding 2-furanone and 2-pyrone derivatives in good-to-high yields. The structure of the 2-furanone was confirmed by single-crystal X-ray crystallography, which revealed that the geometry of the exo-olefin was that of a Z-isomer. When an aromatic ring-substituted alkyne was used, 2-furanone derivatives were selectively obtained via 5-exo-dig cyclization, whereas the reaction of alkyl-substituted alkynes produced 2-pyrone derivatives with high selectivity.
本文言語 | English |
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ページ(範囲) | 5706-5709 |
ページ数 | 4 |
ジャーナル | Organic Letters |
巻 | 17 |
号 | 22 |
DOI | |
出版ステータス | Published - 2015 11月 20 |
ASJC Scopus subject areas
- 生化学
- 物理化学および理論化学
- 有機化学