To explore possible forms of unconventional computers that have high capacities for adaptation and exploration, we propose a new approach to developing a biocomputer based on the photophobic reactions of microbes (Euglena gracilis), and perform the Monte-Carlo simulation of Euglena-based neural network computing, involving virtual optical feedback to the Euglena cells. The photophobic reactions of Euglena are obtained experimentally, and incorporated in the simulation, together with a feedback algorithm with a modified Hopfield-Tank model for solving a 4-city traveling salesman problem. The simulation shows high performances in terms of (1) reaching one of the best solutions of the problem, and (2) searching for a number of solutions via dynamic transition among the solutions. This dynamic transition is attributed to the fluctuation of state variables, global oscillation through feedback instability, and the one-by-one change of state variables.
ASJC Scopus subject areas
- Statistics and Probability
- Modelling and Simulation
- Biochemistry, Genetics and Molecular Biology(all)
- Applied Mathematics